Team
Eunae Sandra Cho
2023~present
Adjunct Scholar, Team leader, Center for Genome Engineering, Institute for Basic Science
2018~present
Assistant professor, Department of Oral Pathology, Yonsei University College of Dentistry
2017~2018
Basic research professor, Department of Oral Pathology, Yonsei University College of Dentistry
2016~2017
Fellow, Department of Oral Pathology, Yonsei University College of Dentistry
Host-virus interactions are complex processes that span binding to cells, entry, dissemination, and finally lytic or latent infection. During infection, host innate immune system restricts viral replication. However, mechanisms underlying viral propagation out of the host surveillance remain unclear.
Our research goal is to understand the molecular basis of virus latency establishment and how it plays a critical role in cellular immune evasion and/or viral reactivation. In addition, we are interested in understanding the role of “the endogenous parasites”, retroelements, in host-virus interaction and innate immunity.
High-resolution mapping of RNA-protein interactions & ultrasensitive and super-resolution proximity labeling proteomics
Our laboratory is working on innovative solutions to combat the degenerative diseases of the musculoskeletal system that inevitably come with aging.
Hyeshik Chang develops and applies transcriptome profiling technologies to explore new RNA regulation mechanisms. His team has specialty in modifying high-throughput sequencing techniques and employing machine learning to identify patterns within large data sets.